"Understanding structure is key to knowing how macromolecules work. Much work has been done in the past decades to solve the shapes of proteins, in order to understand how they function in the cells. Recently, RNA has emerged as another class of important cellular machines, whose function is strongly dictated by its shape. In this talk, Yue will introduce a new technology that allows us to map the shapes of RNA molecules at high speed. Information from this technology provide first glimpses into the organizational rules of RNA shapes and pave the way to understanding how RNA shapes regulate biology."