Xiao Yang

During her Ph.D. and postdoctoral research, Xiao Yang has accumulated unique interdisciplinary expertise, focusing on developing novel bioelectronics technologies to improve the stability of BMIs and expanding into research on regenerative medicine, human neural development, and disease. Starting from material design, she and her team addressed the mismatch between electronics and neurons at multiple levels, including size, mechanical properties, and surface biochemistry.

Inspired by biological systems, she designed and developed a series of bioinspired electronic devices. Among them, the vasculature-like electronic scaffold (VasES) mimics topographical and surface properties of brain vasculature, providing both structural support and biochemical cues for the migration of newborn neurons to the lesion site. For the first time, this achievement demonstrated in vivo neural regeneration, migration, and repair while longitudinally monitoring these processes, opening new avenues for the diagnosis, treatment, and functional restoration of neural damage.

Drawing inspiration from the traditional art of paper cutting, kirigami, she also developed the kirigami-inspired electronics (KiriE). This device can transform from a two-dimensional pattern into a three-dimensional basket-like structure, enabling long-term integration with human brain organoids or assembloids in suspension and providing a new tool for studying complex neural models.

Moving forward, Xiao Yang will continue to explore bioelectronics and neuroengineering platforms, conducting innovative research across molecular, micro, and macro scales to drive new breakthroughs in neural regeneration and brain-machine interfaces.